martedì 10 settembre 2013

Chronic recurrent multifocal osteomyelitis in children


OSTEOMIELITE CRONICA MULTIFOCALE RICORRENTE DELLO SCHELETRO PEDIATRICO


www.siapec.it/content/file/2096/142p_Parafioriti_Milano.ppt

AJR Integrative Imaging
LIFELONG LEARNING
FOR RADIOLOGY
Chronic Recurrent Multifocal Osteomyelitis: Review
Ramesh S. Iyer1, Mahesh M. Thapa1,2, Felix S. Chew1

http://www.ajronline.org/doi/pdf/10.2214/AJR.09.7212

Imaging of Chronic Recurrent Multifocal Osteomyelitis



Abstract

Chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory disorder of children and young adults that is characterized by nonbacterial osteomyelitis. Patients typically present with multifocal bone pain secondary to sterile osseous inflammation, and the disease has a relapsing and remitting course. The cause of CRMO remains unclear, although the results of several studies have suggested a genetic component. The typical imaging findings of CRMO include lytic and sclerotic lesions in the metaphyses of long bones and the medial clavicles. Other common sites of disease are the vertebral bodies, pelvis, ribs, and mandible. CRMO is often bilateral and multifocal at presentation. Owing to the lack of a diagnostic test, CRMO remains a diagnosis of exclusion. Although generally a self-limiting disease, CRMO can have a prolonged course and result in significant morbidity. Radiologists can be the first to suggest this diagnosis given its characteristic radiographic appearance and distribution of disease. Radiologists should be familiar with the typical imaging findings of CRMO to prevent unnecessary multiple biopsies and long-term antibiotic treatment in children with CRMO.
© RSNA, 2009
Chronic Recurrent Multifocal Osteomyelitis (CRMO) (http://www.nomidalliance.org/crmo.php)
Chronic Recurrent Multifocal Osteomyelitis is an autoinflammatory disease that mostly affects children. The causes of the disease have been linked to gene mutations in some cases, especially on chromosome18q in one family. More research is needed on the genetic causes of this challenging condition. 
CRMO presents in patients with periodic fevers, bone pain and bone lesions that can develop anywhere in the body. This is a rare disease, that has been found to affect more girls than boys. The peak for symptom incidence is around 10 years of age, but symptoms can be present from toddler or preschool age to even when patients are on middle age or older. Some patients can have many affected areas in their body, or only a few sites in their body. 
Children will develop deep aching pain, limping, tenderness over affected areas and often fevers. Common sites are the long bones of the body, the collar bone (clavicle) and shoulder girdle. The spine, ankles and feet may also be affected. 
Patients may also present with skin manifestations, such as psoriasis, acne, or pustules on the hands and feet. Some patients may also have uveitis, or inflammatory bowel disease along with CRMO symptoms. Another autoinflammatory disease, Majeed, involves CRMO, but also presents with symptoms of congenital dyserythropoietic anemia and Sweet Syndrome. Majeed is linked to an autosomal recessive inheritance of an LPIN2 gene mutation from both parents, and is a very rare disease. 
Please go to this site for more detailed information on CRMO at this link:http://www.bonetumor.org/tumors-unknown-type/chronic-recurrent-multifocal-osteomyelitis-crmo
Di questo articolo posto solo il titolo, il link e le indicazioni per andarlo a cercare
http://www.ncbi.nlm.nih.gov/pubmed/8034808

 1994 Aug;31(2 Pt 2):376-9.

Pustular psoriasis with chronic recurrent multifocal osteomyelitis and spontaneous fractures.

Source

Department of Dermatology and Pediatrics, Duke University Medical Center, Durham, NC 27710.

Abstract

Chronic recurrent multifocal osteomyelitis is rarely associated with pustular psoriasis in children. We describe a child with severe pustular psoriasis in whom multiple fractures, bone deformities, and severe growth failure from chronic recurrent multifocal osteomyelitis developed. The recurrent fractures led to an incorrect assumption of child abuse. Both the bone disease and pustular psoriasis responded to treatment with etretinate.
PMID:
 
8034808
 
[PubMed - indexed for MEDLINE]

venerdì 6 settembre 2013

TANTO PER TENERLO A MENTE
A MANI FERME
per dire no alle punizioni fisiche nei confronti dei bambini
guarda il video

mercoledì 4 settembre 2013



BES ecco un altro link utile

Il Ministro dell’Istruzione, dell’Università e della Ricerca
STRUMENTI D’INTERVENTO PER ALUNNI CON BISOGNI EDUCATIVI SPECIALI E ORGANIZZAZIONE TERRITORIALE PER L’INCLUSIONE SCOLASTICA 

http://www.marche.istruzione.it/dsa/allegati/dir271212.pdf
ASSENZE
Ecco la circolare ministeriale che regola le assenza scolastiche ai fini della validità dell'anno scolastico (circolare n. 20 del 4 marzo 2011)

http://www.edscuola.eu/wordpress/?wpfb_dl=469

I Bisogni Educativi Speciali
secondo l’ICF (International Classification of Functioning, OMS, 2002) 

Il Bisogno Educativo Speciale (Special Educational Need) è qualsiasi difficoltà evolutiva di funzionamento, permanente o transitoria, in ambito educativo e/o apprenditivo, dovuta all’interazione dei vari fattori di salute secondo il modello ICF dell’OMS, e che necessita di educazione speciale individualizzata

  http://www.omnicomprensivoscigliano.it/starnet/media/BES/ianes.pdf

martedì 3 settembre 2013

OSTEOMIELITE CRONICA MULTIFOCALE RICORRENTE: ELENCO MALATTIE RARE ESENTI DA TICKET

OSTEOMIELITE CRONICA MULTIFOCALE RICORRENTE: ELENCO MALATTIE RARE ESENTI DA TICKET: In questo link trovate l'elenco delle malattie rare esenti da ticket. È disponibile anche sul sito Dell' ISS Ecco il link che trov...

ELENCO MALATTIE RARE ESENTI DA TICKET

In questo link trovate l'elenco delle malattie rare esenti da ticket.
È disponibile anche sul sito Dell' ISS
Ecco il link che troverete anche nella sezione link utili
http://www.iss.it/site/cnmr/dina/mret/et10_tutto.html#